Ricardo Alexandre Spironello1,
Clarissa Botura-Amado1,
Thiely Karine Balensiefer1,
Maria Dalva de Barros Carvalho2,
Darci Aparecida Martins Corrêa3,
Roberto Kenji Nakamura Cuman1 
For correspondence:- Roberto Cuman Email: rkncuman1@gmail.com
Received: 7 July 2015 Accepted: 8 October 2015 Published: 29 November 2015
Citation: Spironello RA, Botura-Amado C, Balensiefer TK, Carvalho MD, Corrêa DA, Cuman RK. A Report on antibiotic management of neonatal sepsis caused by Enterobacter spp. Trop J Pharm Res 2015; 14(11):2131-2134 doi: 10.4314/tjpr.v14i10.26
© 2015 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..
This is a report on a case of neonatal sepsis and clinical management with multiple antibiotic therapy in a neonatal intensive care unit (NICU) in Brazil. A preterm baby boy was born by caesarean section at 34 weeks and two days of gestation from an oligodramnious pregnancy with intrauterine growth restriction. After respiratory failure detection, the baby was intubated and placed on mechanical ventilation for respiratory failure and was shifted to NICU. Ampicillin and gentamicin were instituted empirically. Enterobacter spp-induced severe sepsis was diagnosed. Included in the antibiotic therapy were oxacycline, amikacin, cefepime, tazocin, meropen and teicoplanin. After sixty days in NICU, clinical and laboratory parameters were normalized and the baby recovered. The empirical long-term antibiotic treatment and the use of broad spectrum antibiotics, as observed in the present case, should be carefully considered in newborns admitted to NICU.
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